Products – Glycobar

Commercial Antigens Products

Introduction to blood group antigens

Human red blood cells are covered with blood group antigens :

– If only blood group antigen A is present on the surface of the red blood cells, the blood belongs to “group A”.

– If only blood group antigen B is present on the surface of the red blood cells, the blood belongs to “group B”.

– If both antigens A and B are present on the surface of the red blood cells, the blood belongs to “group AB”.

– If neither antigen is present, the blood belongs to “group O”.

Line 1 of the table below is showing these four different cases:

Blood plasma contains antibodies against the antigens not present on the red cells

– Group A plasma contains anti-B antibodies.

– Group B plasma contains anti-A antibodies.

– Group AB plasma contains neither anti-A nor anti-B antibodies.

– Group O plasma contains both anti-A and anti-B antibodies.

If plasma containing specific antibodies contacts red blood cells with the corresponding antigens, it can destroy the red blood cells, potentially triggering hemolysis.

With universal blood components, blood group antibodies are removed, allowing safe mixing of any blood components, regardless of the donor’s and recipient’s blood groups.

A and B Blood group antigens tetraose sugars

Those are the core products proposed by GlycoBAR.

The standard form is with an amine termination and a linker arm giving to the molecule approximately the same length as the hexa-saccharide blood group antigen sugars corresponding to the natural antigens attached to erythrocytes.

Our two core products are represented below and are available in any quantity at a price that is a small fraction of the competition price for a tri-saccharide.